2ounce tube of Desitin Maximum Strength Diaper Rash Paste with 40zinc oxide works on contact to treat and prevent diaper rash discomfort Rich thick diaper rash cream is formulated with 40 maximumlevel zinc oxide and is clinically shown to protect babys skin for up to 12 hours The 1 choice of Pediatricians and parents it provides effective diaper rash relief by immediately forming a protective barrier on babys skin to seal out wetness and soothe chafed skin Its hypoallergenic formula is paraben phthalate dye and soapfree It is also Dermatologist and Pediatriciantested and is gentle enough for daily use Maximum strength diaper rash paste provides 5in1 action to treat heal protect soothe and prevent diaper rash for healing you can see and relief your baby can feel Based off a clinical study with the Maximum Strength diaper rash paste 90 of babies that used Desitin had noticeable relief within 12 hours Use this baby rash cream to seal out irritants and wetness for ultimate overnight diaper rash relief For best results clean the affected area making sure to avoid further irritating bays skin allowing the area to dry Then apply a thick layer of Desitin diaper rash treatment as needed