The information below applies to each unit in the pack HISTORY OF E45 We released our E45 Cream in 1952 after a customer request for a product that would soothe and protect the skin In 1963 our cream was introduced to pharmacy and retail in 1980 Dermatologically tested Its nongreasy emollient formulation is quickly absorbed by your skin leaving it soft comfortable and relieved Effective and pleasant to use Perfume free HOW TO USE E45 Cream is perfumefree and dermatologically tested it can be used daily by the whole family including infants over the age of 1 month Simply apply to the affected skin 23 times daily and enjoy longlasting moisturisation