Description Previously Available Only by Prescription FDA Approved Once Daily Topical Retinoid Oil Free Fragrance Free Dermatologist Developed and Tested First FDA-approved over-the-counter topical retinoid for acne treatment. Use: For treatment of acne. Suggested use Adults and children 12 years of age and older: Use once daily Clean the skin gently and pat dry before applying the product Cover the entire affected area with a thin layer. For example, if your acne is on the face, apply the product to the entire face. Do not use more than one time a day. Applying more than directed will not provide faster or better results, but may worsen skin irritation.